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Combination antiresorptive and osteoanabolic therapy for osteoporosis: We are not there yet.

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It is even less clear that the benefits of using these drugs to treat women with osteopenia are worth the cost and the potential side effects.

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From the outset, the plan was to pool the data from the two, identically designed studies and from the three alendronate groups in each study, since we anticipated that neither trial alone, nor any one dose group, would be sufficiently large to allow the detection of a significant effect of alendronate on the incidence of new fractures.

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Your statement is analogous to me saying bioidentical hormones such as estradiol causes fatal blood clots, strokes, heart attacks, and breast cancers and should be banned by the FDA.

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